Yukimasa Shiotsu Selected Research

KW 2449

8/2009	KW-2449, a novel multikinase inhibitor, suppresses the growth of leukemia cells with FLT3 mutations or T315I-mutated BCR/ABL translocation.
8/2008	[New therapeutic option for leukemia patients, with FLT3/Aurora kinase inhibitor, KW-2449: strategy and comparison with other kinase inhibitors].

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Yukimasa Shiotsu Research Topics

Disease

17	Neoplasms (Cancer) 01/2022 - 12/2002
7	Breast Neoplasms (Breast Cancer) 06/2010 - 09/2003
3	Multiple Myeloma 03/2015 - 05/2010
3	Leukemia 08/2009 - 08/2007
2	Chromosome Aberrations (Chromosome Abnormalities) 12/2012 - 05/2010
2	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 11/2010 - 08/2007
1	Renal Cell Carcinoma (Grawitz Tumor) 01/2022
1	Stomach Neoplasms (Stomach Cancer) 01/2019
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2018
1	Genetic Translocation (Chromosomal Translocation) 05/2010
1	Carcinoma (Carcinomatosis) 09/2003

Drug/Important Bio-Agent (IBA)

6	Estrogens (Estrogen)FDA Link 06/2010 - 12/2002
5	Phosphotransferases (Kinase)IBA 01/2013 - 08/2008
5	Steryl-Sulfatase (Steroid Sulfatase)IBA 06/2010 - 09/2003
4	Proteins (Proteins, Gene)FDA Link 01/2013 - 10/2003
3	EnzymesIBA 02/2009 - 12/2002
2	Circulating Tumor DNAIBA 01/2022 - 01/2018
2	Heat-Shock Proteins (Heat-Shock Protein)IBA 01/2013 - 05/2010
2	monorden (radicicol)IBA 01/2013 - 10/2003
2	KW-2478IBA 01/2013 - 05/2010
2	Aromatase InhibitorsIBA 06/2010 - 09/2003
2	Hormones (Hormone)IBA 06/2010 - 12/2007
2	Selective Estrogen Receptor Modulators (SERM)IBA 06/2010 - 09/2003
2	Aurora KinasesIBA 08/2009 - 08/2008
2	KW 2449IBA 08/2009 - 08/2008
2	Aromatase (CYP19)IBA 02/2009 - 09/2003
2	Messenger RNA (mRNA)IBA 02/2009 - 09/2003
2	estrone sulfotransferaseIBA 02/2009 - 09/2003
1	NucleotidesIBA 01/2022
1	Immune Checkpoint InhibitorsIBA 01/2022
1	Biomarkers (Surrogate Marker)IBA 01/2022
1	IpilimumabIBA 01/2022
1	DNA (Deoxyribonucleic Acid)IBA 01/2022
1	NivolumabIBA 01/2022
1	Cell-Free Nucleic AcidsIBA 01/2019
1	Proteasome InhibitorsIBA 03/2015
1	shikoninIBA 03/2015
1	geldanamycinIBA 01/2013
1	Adenosine Triphosphate (ATP)IBA 01/2013
1	Molecular Chaperones (Chaperone, Molecular)IBA 01/2013
1	KI 328IBA 11/2010
1	Biological ProductsIBA 05/2010
1	Immunoglobulin Heavy Chains (Immunoglobulin Heavy Chain)IBA 05/2010
1	Green Fluorescent ProteinsIBA 05/2010
1	Histones (Histone)IBA 08/2009
1	Imatinib Mesylate (Gleevec)FDA Link 08/2009
1	KW 2581IBA 12/2007
1	irosustatIBA 12/2007
1	Methylnitrosourea (N-Methyl-N-nitrosourea)IBA 12/2007
1	Tamoxifen FDA LinkGeneric 12/2007
1	flt3 ligand protein (flt3 ligand)IBA 08/2007
1	FI-700IBA 08/2007
1	human ERBB2 proteinIBA 03/2007
1	FucoseIBA 03/2007
1	Trastuzumab (Herceptin)FDA Link 03/2007
1	Pharmaceutical PreparationsIBA 11/2003
1	OximesIBA 10/2003
1	Estrone FDA Link 09/2003
1	Estradiol (Delestrogen)FDA LinkGeneric 09/2003
1	Dehydroepiandrosterone (DHEA)IBA 09/2003
1	Dehydroepiandrosterone SulfateIBA 09/2003
1	SteroidsIBA 12/2002

Therapy/Procedure

6	Therapeutics 01/2022 - 09/2003
2	Oral Administration 08/2009 - 08/2007